Astaxanthin improves lipotoxicity, lipid peroxidation and oxidative stress in kidney of sucrose-rich diet-fed rats. Joubert MBV, Ingaramo PI, Collins P, D’Alessandro ME. J Nutr Biochem. 2024 Oct 5;135:109779. doi: 10.1016/j.jnutbio.2024.109779. Online ahead of print.

Neonatal overfeeding promotes anxiety, impairs episodic-like memory, and disrupts transcriptional regulation of hippocampal steroidogenic enzymes. Rossetti MF, Schumacher R, Canesini G, Fernandez P, Gaydou L, Stoker C, Ramos JG. J Nutr Biochem. 2024 Aug 16:109739. doi: 10.1016/j.jnutbio.2024.109739. Online ahead of print.

Perinatal Exposure to Glyphosate or a Commercial Formulation Alters Uterine Mechanistic Pathways Associated with Implantation Failure in Rats. Almirón A, Lorenz V, Varayoud J, Durando M, Milesi MM Toxics 2024, 12(8), 590. doi: 10.3390/toxics12080590.

Plasma cell-free DNA as a monitoring tool for high-risk pregnancies associated with antiphospholipid syndrome. Cepeda J, Racca ME, Cardozo MA, Gaydou L, Muñoz-de-Toro M, Milesi MM, Varayoud J, Rossetti MF, Ramos JG. Thromb Res. 2024 Jul 31;241:109108. doi: 10.1016/j.thromres.2024.109108. Online ahead of print.

Altered ovarian reserve in Ewe lambs exposed to a glyphosate-based herbicide. Alarcón R, Alegre AL, Rivera O, Dioguardi G, Zenclussen ML, Muñoz-de-Toro M, Luque EH, Ingaramo PI. Chemosphere. 2024 Jul 25;363:142895. doi: 10.1016/j.chemosphere.2024.142895. Online ahead of print.

Glyphosate modifies the gene expression and migration of trophoblastic cells without altering the process of angiogenesis or the implantation of blastocysts in vitro. Oddi S, Altamirano GA, Zenclussen ML, Abud JE, Vaira S, Gomez AL, Schierano-Marotti G, Muñoz-de-Toro M, Kass L. Food Chem Toxicol. 2024 Jul;189:114748. doi: 10.1016/j.fct.2024.114748. Epub 2024 May 18.

Exposure to atrazine and endosulfan alters oviductal adenogenesis in the broad-snouted caiman (Caiman latirostris). Tavalieri Y, Alarcón R, Tschopp M, Luque E, Muñoz-de-Toro M, Galoppo G. Environ Sci Pollut Res Int. 2024 May;31(24):35927-35937. doi: 10.1007/s11356-024-33662-7. Epub 2024 May 14.

Glyphosate-based herbicide worsens alterations induced by cafeteria diet on rat uterus. Zanardi MV, Gastiazoro MP, Rossetti MF, Doná F, Lazzarino GP, Zierau O, Varayoud J, Durando M. J Endocrinol. 2024 Apr 1:JOE-24-0071. doi: 10.1530/JOE-24-0071. Print 2024 Jun 1.

Female offspring of mice perinatally exposed to benzophenone-3 showed early subfertility linked to a poor oocyte stockpile. Galliani V, Abud JE, Zenclussen ML, Rodríguez HA. Arch Toxicol. 2024 Jun;98(6):1909-1918. doi: 10.1007/s00204-024-03730-5. Epub 2024 Mar 30.

In vitro blastocyst implantation and trophoblast migration are disrupted by the UV filter benzophenone-3 (BP3). Abud JE, Pagotto R, Galliani V, Teglia C, Culzoni J, Bollati-Fogolin M, Zenclussen ML, Rodriguez HA. Environ Pollut. 2024 Mar 25:123840. doi: 10.1016/j.envpol.2024.123840. Epub 2024 Mar 25.

Single and combined exposures to bisphenol A and benzophenone-3 during early mouse pregnancy have differential effects on fetal and placental development. Fischer F, Kretschmer T, Seifert P, Howanski J, Krieger E, Rödiger J, Fink B, Yin Z, Bauer M, Zenclussen ML, Meyer N, Schumacher A, Zenclussen AC. Sci Total Environ. 2024 Apr 20;922:171386. doi: 10.1016/j.scitotenv.2024.171386. Epub 2024 Feb 29.

Uterine histopathology and steroid metabolism in a polycystic ovary syndrome rat model. Bracho GS, Acosta MV, Altamirano GA, Alcaraz MR, Montemurro M, Culzoni MJ, Rossetti MF, Kass L, Luque EH, Bosquiazzo VL. Mol Cell Endocrinol. 2024 Mar 11;585:112198. doi: 10.1016/j.mce.2024.112198. Epub 2024 Mar 11.

Absence of Heme Oxygenase-1 Affects Trophoblastic Spheroid Implantation and Provokes Dysregulation of Stress and Angiogenesis Gene Expression in the Uterus. Zenclussen ML, Ulrich S, Bauer M, Fink B, Zenclussen AC, Schumacher A, Meyer N. Cells. 2024 Feb 22;13(5):376. doi: 10.3390/cells13050376.

Branching morphogenesis of the mouse mammary gland after exposure to benzophenone-3. Schierano-Marotti G, Altamirano GA, Oddi S, Gomez AL, Meyer N, Muñoz-de-Toro M, Zenclussen AC, Rodríguez HA, Kass L. Toxicol Appl Pharmacol. 2024 Feb 20;484:116868. doi: 10.1016/j.taap.2024.116868. Epub 2024 Feb 20.

A Reliable Method for Quantifying Plasma Cell-Free DNA Using an Internal Standard Strategy: Evaluation in a Cohort of Non-Pregnant and Pregnant Women. Cepeda J, Racca ME, Rossetti MF, Cardozo MA, Gaydou L, Luque EH, Muñoz-de-Toro M, Milesi MM, Varayoud J, Ramos JG. Reprod Sci. 2024 Apr;31(4):987-996. doi: 10.1007/s43032-023-01403-9. Reprod Sci. 2024 Apr;31(4):987-996. doi: 10.1007/s43032-023-01403-9. Epub 2023 Nov 29.

Effects of Full-Spectrum Cannabis Oil with a Cannabidiol:Tetrahydrocannabinol 2:1 Ratio on the Mechanisms Involved in Hepatic Steatosis and Oxidative Stress in Rats Fed a Sucrose-Rich Diet. Degrave V, Vega Joubert MB, Ingaramo P, Sedan D, Andrinolo D, D’Alessandro ME, Oliva ME. Med Cannabis Cannabinoids. 2023 Nov 15;6(1):170-183. doi: 10.1159/000534610. eCollection 2023 Jan-Dec.

Carbon Monoxide Exposure Does Not Improve The In Vitro Fertilization Rate of Oocytes Obtained from Heterozygous Hmox1 Knockout Mice. Romanelli F, Zenclussen ML, Zenclussen AC, Meyer N. Int J Fertil Steril. 2023 Nov 7;18(1):76-80. doi: 10.22074/IJFS.2023.1982726.1411.

Insulin resistance induced by long-term hyperinsulinemia abolishes the effects of acute insulin exposure on cell-surface nicotinic acetylcholine receptor levels and actin cytoskeleton morphology. García AP, Gaydou L, Pérez E, Barrantes FJ. Biochem Biophys Res Commun. 2023 Dec 10;685:149165. doi: 10.1016/j.bbrc.2023.149165. Epub 2023 Oct 26.

Voces femeninas en la investigación: informes técnicos. Franchi A, Barrancos D, Lardone L, Estepa C, Desuque L, Baima M. Rafaela: Ediciones UNRaf, 2023.

Eje Intestino-Cerebro: ¿cómo se transmite la información desde la madre a la progenie? Rossetti MF.

Neonatal overfeeding alters the functioning of the mesolimbic dopaminergic circuitry involving changes in DNA methylation and effects on feeding behavior. Schumacher R, Rossetti MF, Canesini G, Gaydou L, Garcia AP, Lazzarino GP, Fernandez PR, Stoker C, Carrió MJ, Andreoli MF, Ramos JG. J Nutr Biochem. 2023 Dec;122:109451. doi: 10.1016/j.jnutbio.2023.109451. Epub 2023 Sep 23.

Cannabis oil: Effects on Cannabinoid-Induced Tetrad, blood pressure and metabolic parameters in female rats fed a sucrose-rich diet . Degrave V, Battisti M, Vega Joubert MB, Ingaramo P, Vaccarini C, Sedan D, Andrinolo D, D’Alessandro ME, Oliva ME. Integr Food Nutr Metab. 2023 Jul;10:1-5. doi: 10.15761/IFNM.1000310.

Mammary gland development in male rats perinatally exposed to propiconazole, glyphosate, or their mixture. Gomez AL, Altamirano GA, Alcaraz MR, Montemurro M, Schierano-Marotti G, Oddi SL, Culzoni MJ, Muñoz-de-Toro M, Bosquiazzo VL, Kass L Environ Toxicol Pharmacol. 2023 Aug;101:104184. doi: 10.1016/j.etap.2023.104184. Epub 2023 Jun 14.

Clinical features in cancer patients with COVID-19 in Santa Fe and Buenos Aires, Argentina. Gastiazoro MP, Cardozo MA, Ricardo T, Ramos JG, Ballina A, Maillo M, Bernal MF, Bergero M, Calafell G, Cayol F, Lorenzati C, Mauricio S, Varayoud J J Clin Images Med Case Rep. 2023; 4(2): 2285. doi: 10.52768/2766-7820/2285.

Chapter 10: What Is Caiman latirostris Teaching Us About Endocrine Disruptors? Durando M, Galoppo GH, Tavalieri YE, Zanardi MV, Muñoz-de-Toro M. Edited by: Liwszyc G, Larramendy ML. Bird and Reptile Species in Environmental Risk Assessment Strategies. 2023 Feb 10. doi: 10.1039/BK9781837670765-00169.

Disruption of the developmental programming of the gonad of the broad snouted caiman (Caiman latirostris) after in ovo exposure to atrazine. Canesini G, Galoppo GH, Tavalieri YE, Lazzarino GP, Stoker C, Luque EH, Ramos JG, Muñoz-de-Toro M. Environ Sci Pollut Res Int. 2023 Mar;30(14):40132-40146. doi: 10.1007/s11356-022-25104-z. Epub 2023 Jan 6.

Postnatal exposure to a glyphosate-based herbicide interferes with the development and growth of the mammary gland of pre-pubertal Ewe lambs. Altamirano GA, Masat E, Rivera O, Alarcón R, Dioguardi G, Muñoz-de-Toro M, Luque EH, Kass L. Chemosphere. 2023 Feb;313:137358. doi: 10.1016/j.chemosphere.2022.137358. Epub 2022 Nov 22.

Síndrome de ovario poliquístico: importancia de los inositoles en su terapéutica. Bracho GS, Acosta MV, Luque EH, Bosquiazzo VL. Revista de la Sociedad Argentina de Endocrinología Ginecológica y Reproductiva 2022; Vol. XXIX Nº 2 Julio – diciembre de 2022: 33-44

Introducción a la Biotecnología: sus aplicaciones y alcances. Rossetti MF, Forno AG. Santa Fe: Ediciones UNL, 2022.

Capítulo 1 – Biomarcadores moleculares de interés clínico: investigación y diagnóstico. Rossetti MF, Gaydou L, Follonier A, Ramos JG.
Capítulo 6 – Anticuerpos: una herramienta clave en diagnóstico e investigación. Rossetti MF, Reyes M, Tschopp MV.
Capítulo 13 – El arte de compartir el saber científico: publicación y divulgación. Cardozo MA.

Preceding anti-spike IgG levels predicted risk and severity of COVID-19 during the Omicron-dominant wave in Santa Fe city, Argentina. Eberhardt AT, Simoncini M, Piña C, Galoppo G, Parachú-Marco V, Racca A, Arce S, Viotto E, Facelli F, Valli F, Botto C, Scarpa L, Junges C, Palavecino C, Beccaria C, Sklar D, Mingo G, Genolet A, Muñoz de Toro M, Aimar H, Marignac V, Bossio JC, Armando G, Fernández H, Beldomenico PM. Epidemiol Infect. 2022 Nov 3:150:e187. doi: 10.1017/S0950268822001716.

Dietary Salvia hispanica L. seed counteracted kidney failure in experimental metabolic syndrome. Creus A, Ingaramo P, Oliva ME, D’Alessandro ME. J Food Nutr Metabol. 2022 Oct. doi: 10.31487/j.JFNM.2022.01.03.

Salvia hispanica L. (chia) seed improves liver inflammation and endothelial dysfunction in an experimental model of metabolic syndrome. Vega Joubert MB, Degrave V, Ingaramo P, Oliva ME, D’Alessandro ME. Food Funct. 2022 Oct 31;13(21):11249-11261. doi: 10.1039/d2fo02216h.

Salvia hispanica L. (chia) seed ameliorates liver injury and oxidative stress by modulating NrF2 and NFκB expression in sucrose-rich diet-fed rats. Vega Joubert MB, Ingaramo P, Oliva ME, D’Alessandro ME. Food Funct. 2022 Jul 4;13(13):7333-7345. doi: 10.1039/d2fo00642a

Pleiotropic actions of melatonin in testicular peritubular myoid cells of immature Syrian hamsters. Riviere E, Rossi SP, Tavalieri YE, Muñoz de Toro MM, Calandra RS, Mayerhofer A, Matzkin ME, Frungieri MB. Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130187. doi: 10.1016/j.bbagen.2022.130187. Epub 2022 Jun 9.

Epigenetic disruption of placental genes by chronic maternal cafeteria diet in rats. Gastiazoro MP, Rossetti MF, Schumacher R, Stoker C, Durando M, Zierau O, Ramos JG, Varayoud J. J Nutr Biochem. 2022 Aug;106:109015. doi: 10.1016/j.jnutbio.2022.109015. Epub 2022 Apr 18.

Chapter five: Steroidogenic enzymes in the hippocampus: Transcriptional regulation aspects. Rossetti MF, Varayoud J, Ramos JG. Edited by: Litwack G. Hormones, Regulators and Hippocampus. 2022;118:171-198. doi: 10.1016/bs.vh.2021.11.004. Epub 2022 Feb 7.

Maternal Low-Protein Diet Deregulates DNA Repair and DNA Replication Pathways in Female Offspring Mammary Gland Leading to Increased Chemically Induced Rat Carcinogenesis in Adulthood. Front Cell Dev Biol. 2022 Feb 1;9:756616. Zapaterini JR, Fonseca ARB, Bidinotto LT, Colombelli KT, Rossi ALD, Kass L, Justulin LA, Barbisan LF. doi: 10.3389/fcell.2021.756616. eCollection 2021.

Aberrant Hoxa10 gene methylation as a mechanism for endosulfan-induced implantation failures in rats. Milesi MM, Lorenz V, Varayoud J. Mol Cell Endocrinol. 2022 May 1;547:111576. doi: 10.1016/j.mce.2022.111576. Epub 2022 Jan 31.

AHR agonistic effects of 6-PN contribute to potential beneficial effects of Hops extract. Zanardi MV, Gastiazoro MP, Kretzschmar G, Wober J, Vollmer G, Varayoud J, Durando M, Zierau O. Mol Cell Endocrinol. 2022 Mar 1;543:111540. doi: 10.1016/j.mce.2021.111540. Epub 2021 Dec 26.

Altered uterine angiogenesis in rats treated with a glyphosate-based herbicide. Ingaramo PI, Alarcón R, Caglieris ML, Varayoud J, Muñoz-de-Toro M, Luque EH. Environ Pollut. 2022 Mar 1;296:118729. doi: 10.1016/j.envpol.2021.118729. Epub 2021 Dec 22.

Chapter 7: Pleiotropic Effects of Bisphenol A Alter Milk Synthesis and Production. Altamirano GA, Gomez AL, Kass L. Edited by: Gassman NR. Bisphenol A: A Multi-modal Endocrine Disruptor. The Royal Society of Chemistry. 2022 Jan. doi: 10.1039/9781839166495-00153.

Disruption of developmental programming with long-term consequences after exposure to a glyphosate-based herbicide in a rat model. Guerrero Schimpf M, Milesi MM, Zanardi MV, Varayoud J. Food Chem Toxicol. 2022 Jan;159:112695. doi: 10.1016/j.fct.2021.112695. Epub 2021 Nov 20.

Effects of Salvia hispanica L. (chia) seed on blood coagulation, endothelial dysfunction and liver fibrosis in an experimental model of Metabolic Syndrome. Oliva ME, Ingaramo P, Vega Joubert MB, Ferreira MDR, D’Alessandro ME. Food Funct. 2021 Dec 13;12(24):12407-12420. doi: 10.1039/d1fo02274a.

Editorial: Glyphosate Herbicide as Endocrine Disruptor and Probable Human Carcinogen: Current Knowledge and Future Direction. Lorenz V, Rossetti MF, Dallegrave E, Milesi MM, Varayoud J. Front Endocrinol (Lausanne). 2021 Oct 4;12:772911. doi: 10.3389/fendo.2021.772911. eCollection 2021.

Prenatal exposure to a mixture of different phthalates increases the risk of mammary carcinogenesis in F1 female offspring. de Freitas T, Zapaterini JR, Moreira CM, de Aquino AM, Alonso-Costa LG, Bidinotto LT, Kass L, Flaws JA, Scarano WR, Barbisan LF. Food Chem Toxicol. 2021 Oct;156:112519. doi: 10.1016/j.fct.2021.112519. Epub 2021 Aug 21.

Chronic exposure to low concentrations of chlorpyrifos affects normal cyclicity and histology of the uterus in female rats. Ramos Nieto MR, Lasagna M, Cao G, Álvarez G, Santamaria C, Rodriguez Girault ME, Bourguignon N, Di Giorgio N, Ventura C, Mardirosian M, Rodriguez H, Lux-Llantos V, Cocca C, Núñez M. Food Chem Toxicol. 2021 Oct;156:112515. doi: 10.1016/j.fct.2021.112515. Epub 2021 Aug 14.

Glyphosate Herbicide: Reproductive Outcomes and Multigenerational Effects. Milesi MM, Lorenz V, Durando M, Rossetti MF, Varayoud J. Front Endocrinol (Lausanne). 2021 Jul 7;12:672532. doi: 10.3389/fendo.2021.672532. eCollection 2021.

Desarrollo sostenible en el centro norte de la provincia de Santa Fe. Vol 3: Ambiente. Canal AM, Rodríguez L, Rodríguez HA. Santa Fe: Ediciones UNL, 2021.

Capítulo 5: Efectos del ambiente sobre la salud humana y animal
Introducción (Rodríguez HA)
Efecto del glifosato y sus formulados comerciales sobre el desarrollo de órganos reproductores y la fertilidad (Luque EH, Ingaramo PI)
Estrógenos ambientales y desarrollo y diferenciación mamaria (Altamirano GA, Gomez AL, Kass L)
Contaminantes Ambientales Hormonalmente Activos. Efectos en el sistema reproductor del yacaré overo (Caiman latirostris) (Galoppo GH, Tavalieri YE, Muñoz de Toro M)
Efectos del ambiente sobre la salud humana y animal (Stoker C, Lazzarino GP, Rossetti MF, Ramos JG)

Epigenetic Changes Associated With Exposure to Glyphosate-Based Herbicides in Mammals. Rossetti MF, Canesini G, Lorenz V, Milesi MM, Varayoud J, Ramos JG. Front Endocrinol (Lausanne). 2021 May 21;12:671991. doi: 10.3389/fendo.2021.671991. eCollection 2021.

Exposure to xenoestrogens alters the expression of key morphoregulatory proteins of oviduct adenogenesis in the broad-snouted caiman (Caiman latirostris). Tavalieri YE, Alarcón R, Tschopp MV, Canesini G, Luque EH, Muñoz-de-Toro M, Galoppo GH. Aquat Toxicol. 2021 Jun;235:105817. doi: 10.1016/j.aquatox.2021.105817. Epub 2021 Mar 26.

Evaluation of Development of the Rat Uterus as a Toxicity Biomarker. Guerrero Schimpf M, Milesi MM, Luque EH, Varayoud J. Methods Mol Biol. 2021;2240:103-117. doi: 10.1007/978-1-0716-1091-6_9.

Temporary effects of neonatal overfeeding on homeostatic control of food intake involve alterations in POMC promoter methylation in male rats. Schumacher R, Rossetti MF, Lazzarino GP, Canesini G, García AP, Stoker C, Andreoli MF, Ramos JG. Mol Cell Endocrinol. 2021 Feb 15;522:111123. doi: 10.1016/j.mce.2020.111123. Epub 2020 Dec 15.

Epigenetic regulation of steroidogenic enzymes expressed in peripheral blood mononuclear cells from healthy individuals and from patients with Chronic Lymphocytic Leukemia. Gaydou L, Rossetti MF, Tschopp MV, Stoker C, Bosquiazzo VL, Ramos JG. J Steroid Biochem Mol Biol. 2020 Nov;204:105767. doi: 10.1016/j.jsbmb.2020.105767. Epub 2020 Oct 1.

Perinatal exposure to Bisphenol A disturbs the early differentiation of male germ cells. Pagotto R, Santamaría CG, Harreguy MB, Abud J, Zenclussen ML, Kass L, Crispo M, Muñoz-de-Toro MM, Rodriguez HA, Bollati-Fogolín M. J Steroid Biochem Mol Biol. 2020 Nov;98:117-124. doi: 10.1016/j.reprotox.2020.09.004. Epub 2020 Sep 18.

Bisphenol A and benzophenone-3 exposure alters milk protein expression and its transcriptional regulation during functional differentiation of the mammary gland in vitro. Altamirano GA, Gomez AL, Schierano-Marotti G, Muñoz-de-Toro M, Rodriguez HA, Kass L. Environ Res. 2020 Dec;191:110185. doi: 10.1016/j.envres.2020.110185. Epub 2020 Sep 16.

Androgen receptor and uterine histoarchitecture in a PCOS rat model. Bracho GS, Acosta MV, Altamirano GA, Tschopp MV, Luque EH, Kass L, Bosquiazzo VL. Mol Cell Endocrinol. 2020 Dec 1;518:110973. doi: 10.1016/j.mce.2020.110973. Epub 2020 Aug 8.

Special issue «Health effects of agrochemicals as Endocrine Disruptors». Luque EH, Muñoz-de-Toro M. Mol Cell Endocrinol. 2020 Nov 1;517:110982. doi: 10.1016/j.mce.2020.110982. Epub 2020 Aug 8.

Are glyphosate and glyphosate-based herbicides endocrine disruptors that alter female fertility? Ingaramo P, Alarcón R, Muñoz-de-Toro M, Luque EH. Mol Cell Endocrinol. 2020 Jul 10:110934. doi: 10.1016/j.mce.2020.110934. Epub 2020 Jul 10.

Perinatal exposure to glyphosate or a glyphosate-based formulation disrupts hormonal and uterine milieu during the receptive state in rats. Lorenz V, Pacini G, Luque EH, Varayoud J, Milesi MM. Food Chem Toxicol. 2020 Sep;143:111560. doi: 10.1016/j.fct.2020.111560. Epub 2020 Jul 5.

Melatonin daily oral supplementation attenuates inflammation and oxidative stress in testes of men with altered spermatogenesis of unknown aetiology. Riviere E, Rossi SP, Tavalieri YE, Muñoz de Toro MM, Ponzio R, Puigdomenech E, Levalle O, Martinez G, Terradas C, Calandra RS, Matzkin ME, Frungieri MB. Mol Cell Endocrinol. 2020 Sep 15;515:110889. doi: 10.1016/j.mce.2020.110889. Epub 2020 Jul 3.

Effects of agricultural pesticides on the reproductive system of aquatic wildlife species, with crocodilians as sentinel species. Tavalieri YE, Galoppo GH, Canesini G, Luque EH, Muñoz-de-Toro MM. Mol Cell Endocrinol. 2020 Jun 30:110918. doi: 10.1016/j.mce.2020.110918. Epub 2020 Jun 30.

Neonatal exposure to a glyphosate-based herbicide alters the uterine differentiation of prepubertal ewe lambs. Alarcón R, Rivera OE, Ingaramo PI, Tschopp MV, Dioguardi GH, Milesi MM, Muñoz-de-Toro M, Luque EH. Environ Pollut. 2020 Oct;265(Pt B):114874. doi: 10.1016/j.envpol.2020.114874. Epub 2020 Jun 17.

Correction to: Response to comments on: Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats. Milesi MM, Lorenz V, Beldomenico PM, Vaira S, Varayoud J, Luque EH. Arch Toxicol. 2020 Aug;94(8):2897-2898. doi: 10.1007/s00204-020-02814-2.

Postnatal exposure to endosulfan affects uterine development and fertility. Milesi MM, Durando M, Lorenz V, Gastiazoro MP, Varayoud J. Mol Cell Endocrinol. 2020 Jul 1;511:110855. doi: 10.1016/j.mce.2020.110855. Epub 2020 May 11.

Dermal exposure to the UV filter benzophenone-3 during early pregnancy affects fetal growth and sex ratio of the progeny in mice. Santamaria CG, Meyer N, Schumacher A, Zenclussen ML, Teglia CM, Culzoni MJ, Zenclussen AC, Rodriguez HA. Arch Toxicol. 2020 Aug;94(8):2847-2859. doi: 10.1007/s00204-020-02776-5. Epub 2020 May 19.

Exposure to a Glyphosate-based Herbicide Alters the Expression of Key Regulators of Mammary Gland Development on Pre-pubertal Male Rats. Gomez AL, Altamirano GA, Tschopp MV, Bosquiazzo VL, Muñoz-de-Toro M, Kass L. Toxicology. 2020 Jun;439:152477. doi: 10.1016/j.tox.2020.152477. Epub 2020 Apr 29.

Glyphosate induces epithelial mesenchymal transition-related changes in human endometrial Ishikawa cells via estrogen receptor pathway. Gastiazoro MP, Durando M, Milesi MM, Lorenz V, Vollmer G, Varayoud J, Zierau O. Mol Cell Endocrinol. 2020 Jun 15;510:110841. doi: 10.1016/j.mce.2020.110841. Epub 2020 Apr 28.

Agrochemicals and neurogenesis. Rossetti MF, Stoker C, Ramos JG. Mol Cell Endocrinol. 2020 Jun 15;510:110820. doi: 10.1016/j.mce.2020.110820. Epub 2020 Apr 18.

Long-term effects of in ovo exposure to an environmentally relevant dose of atrazine on the thyroid gland of Caiman latirostris. Galoppo GH, Tavalieri YE, Schierano-Marotti G, Osti MR, Luque EH, Muñoz-de-Toro MM. Environ Res. 2020 Jul;186:109410. doi: 10.1016/j.envres.2020.109410. Epub 2020 Apr 2.

Relationship between agrochemical compounds and mammary gland development and breast cancer. Kass L, Gomez AL, Altamirano GA. Mol Cell Endocrinol. 2020 May 15;508:110789. doi: 10.1016/j.mce.2020.110789. Epub 2020 Mar 9.

AhR ligands reactivate LINE-1 retrotransposon in triple-negative breast cancer cells MDA-MB-231 and non-tumorigenic mammary epithelial cells NMuMG. Miret N, Zappia CD, Altamirano G, Pontillo C, Zárate L, Gómez A, Lasagna M, Cocca C, Kass L, Monczor F, Randi A. Biochem Pharmacol. 2020 May;175:113904. doi: 10.1016/j.bcp.2020.113904. Epub 2020 Mar 8.

Culturing Rat Whole Ovary for UV Filter Benzophenone-3 Treatment. Santamaría CG, Abud JE, Luque EH, Kass L, Rodríguez HA. Curr Protoc Toxicol. 2019 Dec;82(1):e89. doi: 10.1002/cptx.89.

Glyphosate-based herbicide induces hyperplastic ducts in the mammary gland of aging Wistar rats. Zanardi MV, Schimpf MG, Gastiazoro MP, Milesi MM, Muñoz-de-Toro M, Varayoud J, Durando M. Mol Cell Endocrinol. 2020 Feb 5;501:110658. doi: 10.1016/j.mce.2019.110658. Epub 2019 Nov 19.

Response to comments on: Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats. Milesi MM, Lorenz V, Beldomenico PM, Vaira S, Varayoud J, Luque EH. Arch Toxicol. 2019 Dec;93(12):3635-3638. doi: 10.1007/s00204-019-02609-0. Epub 2019 Nov 13.

Epigenetic Dysregulation of Dopaminergic System by Maternal Cafeteria Diet During Early Postnatal Development. Rossetti MF, Schumacher R, Gastiazoro MP, Lazzarino GP, Andreoli MF, Stoker C, Varayoud J, Ramos JG. Neuroscience. 2020 Jan 1;424:12-23. doi: 10.1016/j.neuroscience.2019.09.016. Epub 2019 Nov 1.

Perinatal exposure to bisphenol A (BPA) impairs neuroendocrine mechanisms regulating food intake and kisspetin system in adult male rats. Evidences of metabolic disruptor hypothesis. Stoker C, Andreoli MF, Kass L, Bosquiazzo VL, Rossetti MF, Canesini G, Luque EH, Ramos JG. Mol Cell Endocrinol. 2020 Jan 1;499:110614. doi: 10.1016/j.mce.2019.110614. Epub 2019 Oct 10.

Acute uterine effects and long-term reproductive alterations in postnatally exposed female rats to a mixture of commercial formulations of endosulfan and glyphosate. Ingaramo PI, Guerrero Schimpf M, Milesi MM, Luque EH, Varayoud J. Food Chem Toxicol. 2019 Dec;134:110832. doi: 10.1016/j.fct.2019.110832. Epub 2019 Sep 21.

Cafeteria diet induces progressive changes in hypothalamic mechanisms involved in food intake control at different feeding periods in female rats. Lazzarino GP, Acutain MF, Canesini G, Andreoli MF, Ramos JG. Mol Cell Endocrinol. 2019 Dec 1;498:110542. doi: 10.1016/j.mce.2019.110542. Epub 2019 Aug 17.

Impact of gestational low protein diet and postnatal bisphenol A exposure on chemically induced mammary carcinogenesis in female offspring rats. Varuzza MB, Zapaterini JR, Colombelli KT, Barquilha CN, Justulin LA Jr, Muñoz-de-Toro M, Kass L, Barbisan LF. Environ Toxicol. 2019 Nov;34(11):1263-1272. doi: 10.1002/tox.22827. Epub 2019 Jul 9.

Aging in the Syrian hamster testis: Inflammatory-oxidative status and the impact of photoperiod. Matzkin ME, Valchi P, Riviere E, Rossi SP, Tavalieri YE, Muñoz de Toro MM, Mayerhofer A, Bartke A, Calandra RS, Frungieri MB. Exp Gerontol. 2019 Sep;124:110649. doi: 10.1016/j.exger.2019.110649. Epub 2019 Jul 2.

Exposure to 17α-ethinyl estradiol during early pregnancy affects fetal growth and survival in mice. Meyer N, Santamaria CG, Müller JE, Schumacher A, Rodriguez HA, Zenclussen AC. Environ Pollut. 2019 Aug;251:493-501. doi: 10.1016/j.envpol.2019.04.144. Epub 2019 May 9.

Effect of neonatal exposure to endosulfan on myometrial adaptation during early pregnancy and labor in rats. Alarcón R, Varayoud J, Luque EH, Milesi MM. Mol Cell Endocrinol. 2019 Jul 1;491:110435. doi: 10.1016/j.mce.2019.04.015. Epub 2019 Apr 25.

Methodological aspects of Universal immuno-PCR on standard tubes. Abud JE, Santamaría CG, Oggero M, Rodriguez HA. Anal Biochem. 2019 Apr 1;570:56-61. doi: 10.1016/j.ab.2019.02.007. Epub 2019 Feb 12.

The impact of sensory and motor enrichment on the epigenetic control of steroidogenic-related genes in rat hippocampus. Rossetti MF, Schumacher R, Lazzarino GP, Gomez AL, Varayoud J, Ramos JG. Mol Cell Endocrinol. 2019 Apr 5;485:44-53. doi: 10.1016/j.mce.2019.01.025. Epub 2019 Feb 2.

The UV filter benzophenone 3, alters early follicular assembly in rat whole ovary cultures. Santamaría CG, Abud JE, Porporato MM, Meyer N, Zenclussen AC, Kass L, Rodríguez HA. Toxicol Lett. 2019 Mar 15;303:48-54. doi: 10.1016/j.toxlet.2018.12.016. Epub 2018 Dec 30.

Neonatal exposure to a glyphosate-based herbicide alters the histofunctional differentiation of the ovaries and uterus in lambs. Alarcón R, Ingaramo PI, Rivera OE, Dioguardi GH, Repetti MR, Demonte LD, Milesi MM, Varayoud J, Muñoz-de-Toro M, Luque EH. Mol Cell Endocrinol. 2019 Feb 15;482:45-56. doi: 10.1016/j.mce.2018.12.007. Epub 2018 Dec 11.

Male mammary gland development and methylation status of estrogen receptor alpha in Wistar rats are modified by the developmental exposure to a glyphosate-based herbicide. Gomez AL, Altamirano GA, Leturia J, Bosquiazzo VL, Muñoz-de-Toro M, Kass L. Mol Cell Endocrinol. 2019 Feb 5;481:14-25. doi: 10.1016/j.mce.2018.11.005. Epub 2018 Nov 14.

Epigenetic disruption of estrogen receptor alpha is induced by a glyphosate-based herbicide in the preimplantation uterus of rats. Lorenz V, Milesi MM, Schimpf MG, Luque EH, Varayoud J. Mol Cell Endocrinol. 2019 Jan 15;480:133-141. doi: 10.1016/j.mce.2018.10.022. Epub 2018 Nov 2.

The external genitalia in juvenile Caiman latirostris differ in hormone sex determinate-female from temperature sex determinate-female. Tavalieri YE, Galoppo GH, Canesini G, Truter JC, Ramos JG, Luque EH, Muñoz-de-Toro M. Gen Comp Endocrinol. 2019 Mar 1;273:236-248. doi: 10.1016/j.ygcen.2018.10.003. Epub 2018 Oct 4.

Glyphosate-based herbicide enhances the uterine sensitivity to estradiol in rats. Guerrero Schimpf M, Milesi MM, Luque EH, Varayoud J. J Endocrinol. 2018 Aug 18:JOE-18-0207. doi: 10.1530/JOE-18-0207.

Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats. Milesi MM, Lorenz V, Pacini G, Repetti MR, Demonte LD, Varayoud J, Luque EH. Arch Toxicol. 2018 Aug;92(8):2629-2643. doi: 10.1007/s00204-018-2236-6. Epub 2018 Jun 9.

Hyperandrogenism Induces Histo-Architectural Changes in the Rat Uterus. Bracho GS, Altamirano GA, Kass L, Luque EH, Bosquiazzo VL. Reprod Sci. 2019 May;26(5):657-668. doi: 10.1177/1933719118783881. Epub 2018 Jun 21.

Induction of uterine hyperplasia after cafeteria diet exposure. Gastiazoro MP, Guerrero-Schimpf M, Durando M, Lazzarino GP, Andreoli MF, Zierau O, Luque EH, Ramos JG, Varayoud J. Mol Cell Endocrinol. 2018 Dec 5;477:112-120. doi: 10.1016/j.mce.2018.06.007. Epub 2018 Jun 18.

Bisphenol A exposure during early pregnancy impairs uterine spiral artery remodeling and provokes intrauterine growth restriction in mice. Müller JE, Meyer N, Santamaria CG, Schumacher A, Luque EH, Zenclussen ML, Rodriguez HA, Zenclussen AC. Sci Rep. 2018 Jun 15;8(1):9196. doi: 10.1038/s41598-018-27575-y.

Postnatal exposure to a glyphosate-based herbicide modifies mammary gland growth and development in Wistar male rats. Altamirano GA, Delconte MB, Gomez AL, Ingaramo PI, Bosquiazzo VL, Luque EH, Muñoz-de-Toro M, Kass L. Food Chem Toxicol. 2018 Aug;118:111-118. doi: 10.1016/j.fct.2018.05.011. Epub 2018 May 7.

Evidence Supporting a Role for Constitutive Ghrelin Receptor Signaling in Fasting-Induced Hyperphagia in Male Mice. Fernandez G, Cabral A, Andreoli MF, Labarthe A, M’Kadmi C, Ramos JG, Marie J, Fehrentz JA, Epelbaum J, Tolle V, Perello M. Endocrinology. 2018 Feb 1;159(2):1021-1034. doi: 10.1210/en.2017-03101.

Temperature- vs. estrogen-induced sex determination in Caiman latirostris embryos: Both females, but with different expression patterns of key molecules involved in ovarian development. Canesini G, Stoker C, Galoppo GH, Durando ML, Tschopp MV, Luque EH, Muñoz-de-Toro MM, Ramos JG. Gen Comp Endocrinol. 2018 Apr 1;259:176-188. doi: 10.1016/j.ygcen.2017.11.024. Epub 2017 Nov 29.

Sex- and age-associated differences in episodic-like memory and transcriptional regulation of hippocampal steroidogenic enzymes in rats. Rossetti MF, Varayoud J, Andreoli MF, Stoker C, Luque EH, Ramos JG. Mol Cell Endocrinol. 2018 Jul 15;470:208-218. doi: 10.1016/j.mce.2017.11.001. Epub 2017 Nov 4.

Development of a quantitative immuno-polymerase chain reaction assay to detect and quantify low levels of human thyroid stimulating hormone. Abud JE, Santamaría CG, Luque EH, Rodriguez HA. Anal Biochem. 2017 Dec 15;539:134-143. doi: 10.1016/j.ab.2017.10.023. Epub 2017 Oct 27.

Bisphenol A disrupts the temporal pattern of histofunctional changes in the female reproductive tract of Caiman latirostris. Galoppo GH, Canesini G, Tavalieri YE, Stoker C, Kass L, Luque EH, Muñoz-de-Toro M. Gen Comp Endocrinol. 2017 Dec 1;254:75-85. doi: 10.1016/j.ygcen.2017.09.021. Epub 2017 Sep 22.

Early postnatal exposure to endosulfan interferes with the normal development of the male rat mammary gland. Altamirano GA, Delconte MB, Gomez AL, Alarcón R, Bosquiazzo VL, Luque EH, Muñoz-de-Toro M, Kass L. Toxicol Lett. 2017 Nov 5;281:102-109. doi: 10.1016/j.toxlet.2017.09.012. Epub 2017 Sep 19.

Neonatal exposure to a glyphosate-based herbicide alters uterine decidualization in rats. Ingaramo PI, Varayoud J, Milesi MM, Guerrero Schimpf M, Alarcón R, Muñoz-de-Toro M, Luque EH. Reprod Toxicol. 2017 Oct;73:87-95. doi: 10.1016/j.reprotox.2017.07.022. Epub 2017 Aug 2.

Impaired ovarian response to exogenous gonadotropins in female rat offspring born to mothers perinatally exposed to Bisphenol A. Santamaría CG, Rodriguez HA, Abud JE, Rivera OE, Muñoz-de-Toro M, Luque EH. Reprod Toxicol. 2017 Oct;73:259-268. doi: 10.1016/j.reprotox.2017.06.050. Epub 2017 Jun 23.

Uterine ERα epigenetic modifications are induced by the endocrine disruptor endosulfan in female rats with impaired fertility. Milesi MM, Varayoud J, Ramos JG, Luque EH. Mol Cell Endocrinol. 2017 Oct 15;454:1-11. doi: 10.1016/j.mce.2017.05.028. Epub 2017 May 27.

Cafeteria diet differentially alters the expression of feeding-related genes through DNA methylation mechanisms in individual hypothalamic nuclei. Lazzarino GP, Andreoli MF, Rossetti MF, Stoker C, Tschopp MV, Luque EH, Ramos JG. Mol Cell Endocrinol. 2017 Jul 15;450:113-125. doi: 10.1016/j.mce.2017.05.005. Epub 2017 May 4.

Production of monoclonal antibodies and development of a quantitative immuno-polymerase chain reaction assay to detect and quantify recombinant Glutathione S-transferase. Abud JE, Luque EH, Ramos JG, Rodriguez HA. Protein Expr Purif. 2017 Jul;135:16-23. doi: 10.1016/j.pep.2017.04.014. Epub 2017 Apr 27.

Perinatal Exposure to Bisphenol A or Diethylstilbestrol Increases the Susceptibility to Develop Mammary Gland Lesions After Estrogen Replacement Therapy in Middle-Aged Rats. Gomez AL, Delconte MB, Altamirano GA, Vigezzi L, Bosquiazzo VL, Barbisan LF, Ramos JG, Luque EH, Muñoz-de-Toro M, Kass L. Horm Cancer. 2017 Apr;8(2):78-89. doi: 10.1007/s12672-016-0282-1. Epub 2017 Jan 11.

Perinatal exposure to bisphenol A modifies the transcriptional regulation of the β-Casein gene during secretory activation of the rat mammary gland. Altamirano GA, Ramos JG, Gomez AL, Luque EH, Muñoz-de-Toro M, Kass L. Mol Cell Endocrinol. 2017 Jan 5;439:407-418. doi: 10.1016/j.mce.2016.09.032. Epub 2016 Sep 30.

Dietary withdrawal of phytoestrogens resulted in higher gene expression of 3-beta-HSD and ARO but lower 5-alpha-R-1 in male rats. Andreoli MF, Stoker C, Rossetti MF, Lazzarino GP, Luque EH, Ramos JG. Nutr Res. 2016 Sep;36(9):1004-1012. doi: 10.1016/j.nutres.2016.05.003. Epub 2016 May 7.

Effects of neonatal exposure to a glyphosate-based herbicide on female rat reproduction. Ingaramo PI, Varayoud J, Milesi MM, Schimpf MG, Muñoz-de-Toro M, Luque EH. Reproduction. 2016 Nov;152(5):403-15. doi: 10.1530/REP-16-0171. Epub 2016 Aug 2.

Dietary whey reduces energy intake and alters hypothalamic gene expression in obese phyto-oestrogen-deprived male rats. Andreoli MF, Stoker C, Lazzarino GP, Canesini G, Luque EH, Ramos JG. Br J Nutr. 2016 Sep;116(6):1125-33. doi: 10.1017/S0007114516002865. Epub 2016 Jul 29.

Effects of a glyphosate-based herbicide on the uterus of adult ovariectomized rats. Varayoud J, Durando M, Ramos JG, Milesi MM, Ingaramo PI, Muñoz-de-Toro M, Luque EH. Environ Toxicol. 2017 Apr;32(4):1191-1201. doi: 10.1002/tox.22316. Epub 2016 Jul 27.

Postnatal development and histofunctional differentiation of the oviduct in the broad-snouted caiman (Caiman latirostris). Galoppo GH, Stoker C, Canesini G, Schierano-Marotti G, Durando M, Luque EH, Muñoz-de-Toro M. Gen Comp Endocrinol. 2016 Sep 15;236:42-53. doi: 10.1016/j.ygcen.2016.07.001. Epub 2016 Jul 5.

Oestrogens and Progestagens: Synthesis and Action in the Brain. Rossetti MF, Cambiasso MJ, Holschbach MA, Cabrera R. J Neuroendocrinol. 2016 Jul;28(7). doi: 10.1111/jne.12402.

Neonatal exposure to a glyphosate based herbicide alters the development of the rat uterus. Guerrero Schimpf M, Milesi MM, Ingaramo PI, Luque EH, Varayoud J. Toxicology. 2017 Feb 1;376:2-14. doi: 10.1016/j.tox.2016.06.004. Epub 2016 Jun 7.

Global gene expression and morphological alterations in the mammary gland after gestational exposure to bisphenol A, genistein and indole-3-carbinol in female Sprague-Dawley offspring. Grassi TF, da Silva GN, Bidinotto LT, Rossi BF, Quinalha MM, Kass L, Muñoz-de-Toro M, Barbisan LF. Toxicol Appl Pharmacol. 2016 Jul 15;303:101-109. doi: 10.1016/j.taap.2016.05.004. Epub 2016 May 10.

Pregnancy and lactation differentially modify the transcriptional regulation of steroidogenic enzymes through DNA methylation mechanisms in the hippocampus of aged rats. Rossetti MF, Varayoud J, Lazzarino GP, Luque EH, Ramos JG. Mol Cell Endocrinol. 2016 Jul 5;429:73-83. doi: 10.1016/j.mce.2016.03.037. Epub 2016 Apr 1.

Endosulfan affects uterine development and functional differentiation by disrupting Wnt7a and β-catenin expression in rats. Ingaramo PI, Milesi MM, Schimpf MG, Ramos JG, Vigezzi L, Muñoz-de-Toro M, Luque EH, Varayoud J. Mol Cell Endocrinol. 2016 Apr 15;425:37-47. doi: 10.1016/j.mce.2016.02.011. Epub 2016 Feb 18.

A deregulated expression of estrogen-target genes is associated with an altered response to estradiol in aged rats perinatally exposed to bisphenol A. Vigezzi L, Ramos JG, Kass L, Tschopp MV, Muñoz-de-Toro M, Luque EH, Bosquiazzo VL. Mol Cell Endocrinol. 2016 May 5;426:33-42. doi: 10.1016/j.mce.2016.02.010. Epub 2016 Feb 16.

Revisiting adult neurogenesis and the role of erythropoietin for neuronal and oligodendroglial differentiation in the hippocampus. Hassouna I, Ott C, Wüstefeld L, Offen N, Neher RA, Mitkovski M, Winkler D, Sperling S, Fries L, Goebbels S, Vreja IC, Hagemeyer N, Dittrich M, Rossetti MF, Kröhnert K, Hannke K, Boretius S, Zeug A, Höschen C, Dandekar T, Dere E, Neher E, Rizzoli SO, Nave KA, Sirén AL, Ehrenreich H. Mol Psychiatry. 2016 Dec;21(12):1752-1767. doi: 10.1038/mp.2015.212. Epub 2016 Jan 26.

Ovarian dysfunctions in adult female rat offspring born to mothers perinatally exposed to low doses of bisphenol A. Santamaría C, Durando M, Muñoz de Toro M, Luque EH, Rodriguez HA. J Steroid Biochem Mol Biol. 2016 Apr;158:220-230. doi: 10.1016/j.jsbmb.2015.11.016. Epub 2015 Dec 4.

Histomorphological changes in testes of broad-snouted caimans (Caiman latirostris) associated with in ovo exposure to endocrine-disrupting chemicals. Durando M, Canesini G, Cocito LL, Galoppo GH, Zayas MA, Luque EH, Muñoz-de-Toro M. J Exp Zool A Ecol Genet Physiol. 2016 Jan;325(1):84-96. doi: 10.1002/jez.1999. Epub 2015 Dec 7.

Comparison of energy expenditure, body composition, metabolic disorders, and energy intake between obese children with a history of craniopharyngioma and children with multifactorial obesity. Bomer I, Saure C, Caminiti C, Ramos JG, Zuccaro G, Brea M, Bravo M, Maza C. J Pediatr Endocrinol Metab. 2015 Nov 1;28(11-12):1305-12. doi: 10.1515/jpem-2015-0167.

Characterization of Oct4-GFP transgenic mice as a model to study the effect of environmental estrogens on the maturation of male germ cells by using flow cytometry. Porro V, Pagotto R, Harreguy MB, Ramírez S, Crispo M, Santamaría C, Luque EH, Rodríguez HA, Bollati-Fogolín M. J Steroid Biochem Mol Biol. 2015 Nov;154:53-61. doi: 10.1016/j.jsbmb.2015.06.006. Epub 2015 Jul 4.

Environmental enrichment attenuates the age-related decline in the mRNA expression of steroidogenic enzymes and reduces the methylation state of the steroid 5α-reductase type 1 gene in the rat hippocampus. Rossetti MF, Varayoud J, Moreno-Piovano GS, Luque EH, Ramos JG. Mol Cell Endocrinol. 2015 Sep 5;412:330-8. doi: 10.1016/j.mce.2015.05.024. Epub 2015 May 27.

Milk lipid composition is modified by perinatal exposure to bisphenol A. Altamirano GA, Muñoz-de-Toro M, Luque EH, Gómez AL, Delconte MB, Kass L. Mol Cell Endocrinol. 2015 Aug 15;411:258-67. doi: 10.1016/j.mce.2015.05.007. Epub 2015 May 11.

Neonatal exposure to xenoestrogens impairs the ovarian response to gonadotropin treatment in lambs. Rivera OE, Varayoud J, Rodríguez HA, Santamaría CG, Bosquiazzo VL, Osti M, Belmonte NM, Muñoz-de-Toro M, Luque EH. Reproduction. 2015 Jun;149(6):645-55. doi: 10.1530/REP-14-0567. Epub 2015 Mar 16.

Developmental exposure to bisphenol A alters the differentiation and functional response of the adult rat uterus to estrogen treatment. Vigezzi L, Bosquiazzo VL, Kass L, Ramos JG, Muñoz-de-Toro M, Luque EH. Reprod Toxicol. 2015 Apr;52:83-92. doi: 10.1016/j.reprotox.2015.01.011. Epub 2015 Feb 7.

Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats. Milesi MM, Alarcón R, Ramos JG, Muñoz-de-Toro M, Luque EH, Varayoud J. Mol Cell Endocrinol. 2015 Feb 5;401:248-59. doi: 10.1016/j.mce.2014.11.028. Epub 2014 Dec 5.

Withdrawal of dietary phytoestrogens in adult male rats affects hypothalamic regulation of food intake, induces obesity and alters glucose metabolism. Andreoli MF, Stoker C, Rossetti MF, Alzamendi A, Castrogiovanni D, Luque EH, Ramos JG. Mol Cell Endocrinol. 2015 Feb 5;401:111-9. doi: 10.1016/j.mce.2014.12.002. Epub 2014 Dec 5.

Long-term ovariectomy increases BDNF gene methylation status in mouse hippocampus. Moreno-Piovano GS, Varayoud J, Luque EH, Ramos JG. J Steroid Biochem Mol Biol. 2014 Oct;144 Pt B:243-52. doi: 10.1016/j.jsbmb.2014.08.001. Epub 2014 Aug 4.

Prenatal Bisphenol A exposure delays the development of the male rat mammary gland. Kass L, Durando M, Altamirano GA, Manfroni-Ghibaudo GE, Luque EH, Muñoz-de-Toro M. Reprod Toxicol. 2015 Jul;54:37-46. doi: 10.1016/j.reprotox.2014.02.001. Epub 2014 Feb 22.

[Is there a difference in basic research between animal and human medicine?]. Luque EH. Medicina (B Aires). 2014;74(1):86.

Long-lasting effects of neonatal bisphenol A exposure on the implantation process. Varayoud J, Ramos JG, Muñoz-de-Toro M, Luque EH. Vitam Horm. 2014;94:253-75. doi: 10.1016/B978-0-12-800095-3.00010-9.

The eggshell features and clutch viability of the broad-snouted caiman (Caiman latirostris) are associated with the egg burden of organochlorine compounds. Stoker C, Zayas MA, Ferreira MA, Durando M, Galoppo GH, Rodríguez HA, Repetti MR, Beldoménico HR, Caldini EG, Luque EH, Muñoz-de-Toro M. Ecotoxicol Environ Saf. 2013 Dec;98:191-5. doi: 10.1016/j.ecoenv.2013.08.022. Epub 2013 Sep 19.

Neonatal expression of amh, sox9 and sf-1 mRNA in Caiman latirostris and effects of in ovo exposure to endocrine disrupting chemicals. Durando M, Cocito L, Rodríguez HA, Varayoud J, Ramos JG, Luque EH, Muñoz-de-Toro M. Gen Comp Endocrinol. 2013 Sep 15;191:31-8. doi: 10.1016/j.ygcen.2013.05.013. Epub 2013 Jun 4.

Perinatal exposure to diethylstilbestrol alters the functional differentiation of the adult rat uterus. Bosquiazzo VL, Vigezzi L, Muñoz-de-Toro M, Luque EH. J Steroid Biochem Mol Biol. 2013 Nov;138:1-9. doi: 10.1016/j.jsbmb.2013.02.011. Epub 2013 Feb 28.

Sexually dimorphic expression of receptor-alpha in the cerebral cortex of neonatal Caiman latirostris (Crocodylia: Alligatoridae). Varayoud J, Monje L, Moreno-Piovano GS, Galoppo GH, Luque EH, Muñoz-de-Toro M, Ramos JG. Gen Comp Endocrinol. 2012 Nov 1;179(2):205-13. doi: 10.1016/j.ygcen.2012.08.019. Epub 2012 Aug 31.

Perinatal exposure to xenoestrogens impairs mammary gland differentiation and modifies milk composition in Wistar rats. Kass L, Altamirano GA, Bosquiazzo VL, Luque EH, Muñoz-de-Toro M. Reprod Toxicol. 2012 Jun;33(3):390-400. doi: 10.1016/j.reprotox.2012.02.002. Epub 2012 Feb 13.

Neonatal exposure to low doses of endosulfan disrupts the expression of proteins regulating uterine development and differentiation. Milesi MM, Varayoud J, Bosquiazzo VL, Muñoz-de-Toro M, Luque EH. Reprod Toxicol. 2012 Jan;33(1):85-93. doi: 10.1016/j.reprotox.2011.12.003. Epub 2011 Dec 17.

Neonatal exposure to bisphenol A or diethylstilbestrol alters the ovarian follicular dynamics in the lamb. Rivera OE, Varayoud J, Rodríguez HA, Muñoz-de-Toro M, Luque EH. Reprod Toxicol. 2011 Nov;32(3):304-12. doi: 10.1016/j.reprotox.2011.06.118. Epub 2011 Jun 21.

Organochlorine compound residues in the eggs of broad-snouted caimans (Caiman latirostris) and correlation with measures of reproductive performance. Stoker C, Repetti MR, García SR, Zayas MA, Galoppo GH, Beldoménico HR, Luque EH, Muñoz-de-Toro M. Chemosphere. 2011 Jun;84(3):311-7. doi: 10.1016/j.chemosphere.2011.04.013. Epub 2011 May 4.

Prenatal exposure to bisphenol A promotes angiogenesis and alters steroid-mediated responses in the mammary glands of cycling rats. Durando M, Kass L, Perdomo V, Bosquiazzo VL, Luque EH, Muñoz-de-Toro M. J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):35-43. doi: 10.1016/j.jsbmb.2011.04.001. Epub 2011 Apr 14.

Demasculinization and feminization of male gonads by atrazine: consistent effects across vertebrate classes. Hayes TB, Anderson LL, Beasley VR, de Solla SR, Iguchi T, Ingraham H, Kestemont P, Kniewald J, Kniewald Z, Langlois VS, Luque EH, McCoy KA, Muñoz-de-Toro M, Oka T, Oliveira CA, Orton F, Ruby S, Suzawa M, Tavera-Mendoza LE, Trudeau VL, Victor-Costa AB, Willingham E. J Steroid Biochem Mol Biol. 2011 Oct;127(1-2):64-73. doi: 10.1016/j.jsbmb.2011.03.015. Epub 2011 Mar 23.

One-step derivatization and preconcentration microextraction technique for determination of bisphenol A in beverage samples by gas chromatography-mass spectrometry. Fontana AR, Muñoz de Toro M, Altamirano JC. J Agric Food Chem. 2011 Apr 27;59(8):3559-65. doi: 10.1021/jf104622x. Epub 2011 Apr 4.

Neonatal exposure to bisphenol A alters rat uterine implantation-associated gene expression and reduces the number of implantation sites. Varayoud J, Ramos JG, Bosquiazzo VL, Lower M, Muñoz-de-Toro M, Luque EH. Endocrinology. 2011 Mar;152(3):1101-11. doi: 10.1210/en.2009-1037. Epub 2011 Feb 1.

Exposure of neonatal female rats to bisphenol A disrupts hypothalamic LHRH pre-mRNA processing and estrogen receptor alpha expression in nuclei controlling estrous cyclicity. Monje L, Varayoud J, Muñoz-de-Toro M, Luque EH, Ramos JG. Reprod Toxicol. 2010 Dec;30(4):625-34. doi: 10.1016/j.reprotox.2010.08.004. Epub 2010 Oct 15.

Neonatal exposure to bisphenol A reduces the pool of primordial follicles in the rat ovary. Rodríguez HA, Santambrosio N, Santamaría CG, Muñoz-de-Toro M, Luque EH. Reprod Toxicol. 2010 Dec;30(4):550-7. doi: 10.1016/j.reprotox.2010.07.008. Epub 2010 Aug 6.

Matrix crosslinking forces tumor progression by enhancing integrin signaling. Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. Cell. 2009 Nov 25;139(5):891-906. doi: 10.1016/j.cell.2009.10.027.

Effects of neonatal exposure to bisphenol A on steroid regulation of vascular endothelial growth factor expression and endothelial cell proliferation in the adult rat uterus. Bosquiazzo VL, Varayoud J, Muñoz-de-Toro M, Luque EH, Ramos JG. Biol Reprod. 2010 Jan;82(1):86-95. doi: 10.1095/biolreprod.109.078543. Epub 2009 Aug 19.

Neonatal exposure to bisphenol A alters estrogen-dependent mechanisms governing sexual behavior in the adult female rat. Monje L, Varayoud J, Muñoz-de-Toro M, Luque EH, Ramos JG. Reprod Toxicol. 2009 Dec;28(4):435-42. doi: 10.1016/j.reprotox.2009.06.012. Epub 2009 Jul 3.

Prenatal exposure to pesticides disrupts testicular histoarchitecture and alters testosterone levels in male Caiman latirostris. Rey F, González M, Zayas MA, Stoker C, Durando M, Luque EH, Muñoz-de-Toro M. Gen Comp Endocrinol. 2009 Jul;162(3):286-92. doi: 10.1016/j.ygcen.2009.03.032. Epub 2009 Apr 11.

Endosulfan modulates estrogen-dependent genes like a non-uterotrophic dose of 17beta-estradiol. Varayoud J, Monje L, Bernhardt T, Muñoz-de-Toro M, Luque EH, Ramos JG. Reprod Toxicol. 2008 Oct;26(2):138-45. doi: 10.1016/j.reprotox.2008.08.004. Epub 2008 Aug 23.

Developmental exposure to Bisphenol a impairs the uterine response to ovarian steroids in the adult. Varayoud J, Ramos JG, Bosquiazzo VL, Muñoz-de-Toro M, Luque EH. Endocrinology. 2008 Nov;149(11):5848-60. doi: 10.1210/en.2008-0651. Epub 2008 Jul 24.

Regional changes in the spatio-temporal pattern of progesterone receptor (PR) expression in the guinea-pig genital tract as parturition approaches. Rodríguez HA, Ramos JG, Ortega HH, Muñoz-de-Toro M, Luque EH. J Steroid Biochem Mol Biol. 2008 Sep;111(3-5):247-54. doi: 10.1016/j.jsbmb.2008.06.012. Epub 2008 Jun 26.

Developmental exposure to endocrine disruptor chemicals alters follicular dynamics and steroid levels in Caiman latirostris. Stoker C, Beldoménico PM, Bosquiazzo VL, Zayas MA, Rey F, Rodríguez H, Muñoz-de-Toro M, Luque EH. Gen Comp Endocrinol. 2008 May 1;156(3):603-12. doi: 10.1016/j.ygcen.2008.02.011. Epub 2008 Feb 29.

Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. Kass L, Erler JT, Dembo M, Weaver VM. Int J Biochem Cell Biol. 2007;39(11):1987-94. doi: 10.1016/j.biocel.2007.06.025. Epub 2007 Jul 19.

Mast cell degranulation in rat uterine cervix during pregnancy correlates with expression of vascular endothelial growth factor mRNA and angiogenesis. Bosquiazzo VL, Ramos JG, Varayoud J, Muñoz-de-Toro M, Luque EH. Reproduction. 2007 May;133(5):1045-55. doi: 10.1530/REP-06-0168.

Neonatal exposure to bisphenol A modifies the abundance of estrogen receptor alpha transcripts with alternative 5′-untranslated regions in the female rat preoptic area. Monje L, Varayoud J, Luque EH, Ramos JG. J Endocrinol. 2007 Jul;194(1):201-12. doi: 10.1677/JOE-07-0014.

Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats. Durando M, Kass L, Piva J, Sonnenschein C, Soto AM, Luque EH, Muñoz-de-Toro M. Environ Health Perspect. 2007 Jan;115(1):80-6. doi: 10.1289/ehp.9282.

Diethylstilbestrol alters the population dynamic of neural precursor cells in the neonatal male rat dentate gyrus. Ramos JG, Varayoud J, Monje L, Moreno-Piovano G, Muñoz-de-Toro M, Luque EH. Brain Res Bull. 2007 Mar 30;71(6):619-27. doi: 10.1016/j.brainresbull.2006.12.004. Epub 2007 Jan 4.

In ovum exposure to pesticides increases the egg weight loss and decreases hatchlings weight of Caiman latirostris (Crocodylia: Alligatoridae). Beldomenico PM, Rey F, Prado WS, Villarreal JC, Muñoz-de-Toro M, Luque EH. Ecotoxicol Environ Saf. 2007 Oct;68(2):246-51. doi: 10.1016/j.ecoenv.2006.12.018. Epub 2007 Feb 5.

Estrogenic microenvironment generated by organochlorine residues in adipose mammary tissue modulates biomarker expression in ERalpha-positive breast carcinomas. Muñoz-de-Toro M, Durando M, Beldoménico PM, Beldoménico HR, Kass L, García SR, Luque EH. Breast Cancer Res. 2006;8(4):R47. doi: 10.1186/bcr1534.

Organochlorine levels in adipose tissue of women from a littoral region of Argentina. Muñoz-de-Toro M, Beldoménico HR, García SR, Stoker C, De Jesús JJ, Beldoménico PM, Ramos JG, Luque EH. Environ Res. 2006 Sep;102(1):107-12. doi: 10.1016/j.envres.2005.12.017. Epub 2006 Feb 9.

Vitellogenin detection in Caiman latirostris (Crocodylia: Alligatoridae): a tool to assess environmental estrogen exposure in wildlife. Rey F, Ramos JG, Stoker C, Bussmann LE, Luque EH, Muñoz-de-Toro M. J Comp Physiol B. 2006 Mar;176(3):243-51. doi: 10.1007/s00360-005-0045-8. Epub 2005 Nov 15.

The estrogen receptor alpha sigma3 mRNA splicing variant is differentially regulated by estrogen and progesterone in the rat uterus. Varayoud J, Ramos JG, Monje L, Bosquiazzo V, Muñoz-de-Toro M, Luque EH. J Endocrinol. 2005 Jul;186(1):51-60. doi: 10.1677/joe.1.06099.

Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice. Muñoz-de-Toro M, Markey CM, Wadia PR, Luque EH, Rubin BS, Sonnenschein C, Soto AM. Endocrinology. 2005 Sep;146(9):4138-47. doi: 10.1210/en.2005-0340. Epub 2005 May 26.

Macrophage density in the pregnant rat uterine cervix is modulated by mast cell degranulation. Bosquiazzo VL, Durando M, Varayoud J, Ramos JG, Rodríguez HA, Muñoz-de-Toro M, Luque EH. J Reprod Immunol. 2005 Apr;65(2):147-58. doi: 10.1016/j.jri.2005.01.002.

Association of increased estrogen receptor beta2 expression with parity-induced alterations in the rat mammary gland. Kass L, Durando M, Ramos JG, Varayoud J, Powell CE, Luque EH, Muñoz-de-Toro M. J Steroid Biochem Mol Biol. 2004 Jun;91(1-2):29-39. doi: 10.1016/j.jsbmb.2004.02.001.

Mast cells degranulation affects angiogenesis in the rat uterine cervix during pregnancy. Varayoud J, Ramos JG, Bosquiazzo VL, Muñoz-de-Toro M, Luque EH. Reproduction. 2004 Mar;127(3):379-87. doi: 10.1530/rep.1.00018.

Guinea-pig interpubic joint (symphysis pubica) relaxation at parturition: underlying cellular processes that resemble an inflammatory response. Rodríguez HA, Ortega HH, Ramos JG, Muñoz-de-Toro M, Luque EH. Reprod Biol Endocrinol. 2003 Nov 21;1:113. doi: 10.1186/1477-7827-1-113.

Collagen remodelling in the guinea-pig uterine cervix at term is associated with a decrease in progesterone receptor expression. Rodríguez HA, Kass L, Varayoud J, Ramos JG, Ortega HH, Durando M, Muñoz-De-Toro M, Luque EH. Mol Hum Reprod. 2003 Dec;9(12):807-13. doi: 10.1093/molehr/gag099.

Sex reversal effects on Caiman latirostris exposed to environmentally relevant doses of the xenoestrogen bisphenol A. Stoker C, Rey F, Rodriguez H, Ramos JG, Sirosky P, Larriera A, Luque EH, Muñoz-de-Toro M. Gen Comp Endocrinol. 2003 Oct 1;133(3):287-96. doi: 10.1016/s0016-6480(03)00199-0.

Bisphenol a induces both transient and permanent histofunctional alterations of the hypothalamic-pituitary-gonadal axis in prenatally exposed male rats. Ramos JG, Varayoud J, Kass L, Rodríguez H, Costabel L, Muñoz-De-Toro M, Luque EH. Endocrinology. 2003 Jul;144(7):3206-15. doi: 10.1210/en.2002-0198.

Morphological characteristics of the interpubic joint (Symphysis pubica) of rats, guinea pigs and mice in different physiological situations. A comparative study. Ortega HH, Muñoz-de-Toro MM, Luque EH, Montes GS. Cells Tissues Organs. 2003;173(2):105-14. doi: 10.1159/000068947.

Phenotypic modulation of fibroblastic cells in the mucous layer of the human uterine cervix at term. Montes GS, Zugaib M, Joazeiro PP, Varayoud J, Ramos JG, Muñoz-de-Toro M, Luque EH. Reproduction. 2002 Dec;124(6):783-90. doi: 10.1530/rep.0.1240783.

Cellular turnover in the rat uterine cervix and its relationship to estrogen and progesterone receptor dynamics. Ramos JG, Varayoud J, Bosquiazzo VL, Luque EH, Muñoz-de-Toro M. Biol Reprod. 2002 Sep;67(3):735-42. doi: 10.1095/biolreprod.101.002402.

Differential distribution of the fibres of the collagenous and elastic systems and of glycosaminoglycans in the rat pubic joint. Ortega HH, Joazeiro PP, Muñoz-de-Toro MM, Luque EH, Montes GS. J Submicrosc Cytol Pathol. 2001 Oct;33(4):463-72.

Relaxin has a minor role in rat mammary gland growth and differentiation during pregnancy. Kass L, Ramos JG, Ortega HH, Montes GS, Bussmann LE, Luque EH, Muñoz de Toro M. Endocrine. 2001 Aug;15(3):263-9. doi: 10.1385/endo:15:3:263.

Prenatal exposure to low doses of bisphenol A alters the periductal stroma and glandular cell function in the rat ventral prostate. Ramos JG, Varayoud J, Sonnenschein C, Soto AM, Muñoz De Toro M, Luque EH. Biol Reprod. 2001 Oct;65(4):1271-7. doi: 10.1095/biolreprod65.4.1271.

In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland. Markey CM, Luque EH, Munoz De Toro M, Sonnenschein C, Soto AM. Biol Reprod. 2001 Oct;65(4):1215-23. doi: 10.1093/biolreprod/65.4.1215.

Bcl-2 correlates with tumor ploidy and nuclear morphology in early stage prostate carcinoma. A fine needle aspiration biopsy study. Maffini MV, Ortega HH, Stoker C, Giardina RH, Luque EH, Muñoz de Toro MM. Pathol Res Pract. 2001;197(7):487-92. doi: 10.1078/0344-0338-00116.

Characterization of fibroblastic cell plasticity in the lamina propria of the rat uterine cervix at term. Varayoud J, Ramos JG, Joazeiro PP, Montes GS, Muñoz De Toro MM, Luque EH. Biol Reprod. 2001 Aug;65(2):375-83. doi: 10.1095/biolreprod65.2.375.

Detection of bromodeoxyuridine in formalin-fixed tissue. DNA denaturation following microwave or enzymatic digestion pretreatment is required. Kass L, Varayoud J, Ortega H, Muñoz de Toro M, Luque EH. Eur J Histochem. 2000;44(2):185-91.

Estrogen and progesterone modulation of eosinophilic infiltration of the rat uterine cervix. Ramos JG, Varayoud J, Kass L, Rodriguez H, Muñoz de Toro M, Montes GS, Luque EH. Steroids. 2000 Jul;65(7):409-14. doi: 10.1016/s0039-128x(00)00098-2.

Proliferative activity and steroid hormone receptor status in male breast carcinoma. Muñoz de Toro MM, Maffini MV, Kass L, Luque EH. J Steroid Biochem Mol Biol. 1998 Nov;67(4):333-9. doi: 10.1016/s0960-0760(98)00124-1.

Processing fine needle aspirates of prostate carcinomas for standard immunocytochemical studies and in situ apoptosis detection. Muñoz de Toro M, Maffini MV, Giardina RH, Luque EH. Pathol Res Pract. 1998;194(9):631-6. doi: 10.1016/s0344-0338(98)80098-8.

Role of relaxin and estrogen in the control of eosinophilic invasion and collagen remodeling in rat cervical tissue at term. Luque EH, Muñoz de Toro MM, Ramos JG, Rodriguez HA, Sherwood OD. Biol Reprod. 1998 Oct;59(4):795-800. doi: 10.1095/biolreprod59.4.795.

[Male breast carcinoma: prognostic and predictive factors related to biological behavior]. Luque EH, Muñoz de Toro M. Medicina (B Aires). 1998;58(1):95-105.

Leukocyte infiltration and collagenolysis in cervical tissue from intrapartum sheep. Luque EH, Bassani MM, Ramos JG, Maffini M, Canal A, Kass L, Caldini EG, Ferreira Júnior JM, Muñoz de Toro M, Montes GS. Zentralbl Veterinarmed A. 1997 Oct;44(8):501-10. doi: 10.1111/j.1439-0442.1997.tb01136.x.

Lack of relationship between the expression of Hsp27 heat shock estrogen receptor-associated protein and estrogen receptor or progesterone receptor status in male breast carcinoma. Muñoz de Toro MM, Luque EH. J Steroid Biochem Mol Biol. 1997 Mar;60(5-6):277-84. doi: 10.1016/s0960-0760(96)00221-x.

Dissociation in the control of cervical eosinophilic infiltration and collagenolysis at the end of pregnancy or after pseudopregnancy in ovariectomized steroid-treated rats. Luque EH, Ramos JG, Rodriguez HA, Muñoz de Toro MM. Biol Reprod. 1996 Dec;55(6):1206-12. doi: 10.1095/biolreprod55.6.1206.

Correlation of thyrotropin secretion with morphometric data of secretory granules from individual thyrotropes. An ultrastructural study on rat cells identified by reverse hemolytic plaque assay. Caldini N, Muñoz de Toro M, Montes GS, Luque EH. Arch Histol Cytol. 1996 May;59(2):149-58. doi: 10.1679/aohc.59.149.

Subpopulations of lactotropes detected with the reverse hemolytic plaque assay show differential responsiveness to dopamine. Luque EH, Munoz de Toro M, Smith PF, Neill JD. Endocrinology. 1986 May;118(5):2120-4. doi: 10.1210/endo-118-5-2120.

Detection and measurement of hormone secretion from individual pituitary cells. Neill JD, Smith PF, Luque EH, Munoz de Toro M, Nagy G, Mulchahey JJ. Recent Prog Horm Res. 1987;43:175-229. doi: 10.1016/b978-0-12-571143-2.50011-3.